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教授

陈学伟

时间:2014-07-21  来源:四川农业大学 太阳集团7237网站   点击数:

陈学伟:博士,特聘教授, 研究员,博士生导师,四川省“百人计划”特聘专家,四川省学术带头人,教育部“新世纪优秀人才”。

四川农业大学茶学93级学士、作物遗传育种专业97级硕士(四川农业大学/中国科学院遗传与发育生物所联合培养),于2003年在中国科学院遗传与发育生物所获得博士学位。于2004年赴美,先后在加州大学-欧文分校、加州大学-戴维斯分校从事博士后研究工作;于2009年晋升为加州大学-戴维斯分校助理项目科学家。20113月回国作为四川农业大学首批高端人才(特聘教授)进入四川农业大学工作;201112月入选四川省引进海外高层次人才“百人计划”特聘专家;2013年入选四川省第十批学术与技术带头人;2103年入选教育部“新世纪优秀人才”。作为主研人员主持或参与了国内自然科学基金、973863、科技部转基因专项等项目以及美国国家自然科学基金(NSF)、美国国家卫生研究所(NIH)、美国能源部(DOE)等赞助的重大项目,并在Science, Proceedings of the National Academy of SciencesPLoS BiologyPLoS Genet, The Plant JournalMolecular Plant, Plant physiology, Journal of Biological ChemistryPLoS OneGeneticsPlant Molecular Biology等国际顶级杂志和科学通报,遗传学报,生物工程学报等国内重要核心期刊上发表论文共30余篇,获得四川省科学技术进步一等奖一项,申请国家发明专利两项并获授权,并申请美国国家发明专利两项。

主要研究方向:

利用遗传学,分子生物学,植物病理学,生物化学,生物信息学等多学科知识和技术手段对水稻抗病虫害及其他重要农艺性性状控制基因的分子克隆及分子作用机制研究,为培育高抗、高产、优质水稻品种提供理论及应用基础。

发表的主要论著:

1 Xuewei Chen*, Shimin Zuo , Benjamin Schwessinger, Mawsheng Chern, Patrick E. Canlas, Deling Ruan, Xiaogang zhou, Jing Wang, Arsalan Daudi, Christopher J. Petzold, Joshua L. Heazlewood and Pamela C. Ronald*. 2014 An XA21-Associated Kinase (OsSERK2) regulates immunity mediated by the XA21 and XA3 immune receptors, Molecular Plant doi:10.1093/mp/ssu003

2 Xuewei Chen, Miguel E. Vega-Sánchez, Yves Verhertbruggen, Dawn Chiniquy, Patrick E. Canlas, Alexandra Fagerström, Lina Prak, Ulla Christensen, Ai Oikawa, Mawsheng Chen, Shimin Zuo, Fan Lin, Manfred Auer, William G.T. Willats, Laura Bartley, Jesper Harholt, Henrik V. Scheller, and Pamela C. Ronald. 2012 Inactivation of OsIRX10 leads to decreased xylan content in ricestem cell walls and improved biomass saccharification. Molecular Plant 6(1): doi: 10.1093/mp/sss135.

3 Mawsheng Chern, Wei Bai, Xuewei Chen, Pamela Ronald. 2013, Reduced expression of glycolate oxidase leads to enhanced disease resistance in rice. Peer Journal 1:e28. doi: 10.7717/peerj.28.

4 Miguel E. Vega-Sánchez, Yves Verhertbruggen, Ulla Christensen, Xuewei Chen, Vaishali Sharma, Patanjali Varanasi, Stephen A. Jobling, Mark Talbot, Rosemary G. White, Michael Joo, Seema Singh, Manfred Auer, Henrik V. Scheller and Pamela C. Ronald. 2012, Loss of Cellulose Synthase-Like F6 Function Affects Mixed-Linkage Glucan Deposition, Cell Wall Mechanical Properties, and Defense Responses in Vegetative Tissues of Rice. Plant Physiology 159:56-69.

5 Xuewei Chen and Pamela C. Ronald. 2011, Innate immunity in rice. Trends in Plant Science.16:451-459.

6 Xuewei Chen, Mawsheng Chern, Patric E. Canlas, Deling Ruan, Caiying Jiang, Pamela C. Ronald. 2010, The rice XB24 ATPase promotes autophosphorylation of XA21 and inhibits XA21-mediated immunity. Proceedings of the National Academy of Sciences Track II.10780298034.

7 Xuewei Chen, Mawsheng Chern, Patric E. Canlas, Deling Ruan, Caiying Jiang, Pamela C. Ronald A conserved threonine residue in the juxtamembrane domain of the XA21 pattern recognition receptor is critical for kinase autophosphorylation and XA21-mediated immunity. 2010, Journal of Biological Chemistry. 285: 10454-10463.

8 Junjun Shang, Yong Tao, Xuewei Chen (co-first author), Yan Zou, Cailin Lei, Jing Wang, Xiaobing Li, Xianfeng Zhao, Meijun Zhang, Zhike Lu, Jichen Xu, Zhukuan Cheng, Jianmin Wan, Lihuang Zhu. 2009, Identification of a new rice blast resistance gene, Pid3, by genome-wide comparison of paired NBS-LRR genes and their pseudogene alleles between the two sequenced rice genomes. Genetics, 1821303-1311.

9 Xuewei Chen, Junjun Shang, Cailin Lei, Jichen Xu, Shigui Li, Lihuang Zhu. 2008. Genetic and Molecular Analyses of Blast Resistance in a Universal Blast Resistant Variety, Digu. G.-L. Wang, B. Valent (eds.) Advances in Genetics, Genomics and Control of Rice Blast Disease, 149-159.

10 Xuewei Chen, Junjun Shang, Dexi Chen, Cailin Lei, Yan Zou, Wenxue Zhai, Guozhen Liu, Jichen Xu, Zhongzhuan Ling, Gang Cao, Bingtian Ma, Yuping Wang, Xianfeng Zhao, Shigui Li, Lihuang Zhu. 2006, A B-lectin receptor kinase gene conferring rice blast resistance. The Plant Journal, 46 (5), 794–804.

11 Chang-Jin Park, Ying Peng, Xuewei Chen, Christopher Dardick, DeLing Ruan, Rebecca Bart, Patrick E. Canlas, Pamela C. Ronald. 2008, Rice XB15, a Protein Phosphatase 2C, Negatively Regulates Cell Death and XA21-Mediated Innate Immunity. PLoS Biology, 6(9) e231.

12 Chang-Jin Park, Sang-Wook Han, Xuewei Chen, and Pamela C. Ronald. 2010, Elucidation of XA21-mediated innate immunity. Cellular Microbiology, 12(8):1017-25.

13 CHEN De-xi, CHEN Xue-wei, MA Bing-tian, WANG Yu-ping, ZHU Li-huang, LI Shi-gui. 2010, Genetic Transformation of Rice with Pi-d2 Gene Enhances Resistance to Rice Blast Fungus Magnaporthe oryzae. Rice Science, 17(1)

14 Ying Peng, Laura E. Bartley, Xuewei Chen, Christopher Dardick, Mawsheng Chern, Randy Ruan, Patrick E. Canlas, Pamela C. Ronald. 2008, OsWRKY62 is a Negative Regulator of Basal and Xa21-Mediated Defense against Xanthomonas oryzae pv. oryzae in Rice. Molecular Plant. 1: 446-458.

15 Lei Li, Xiangfeng Wang, Rajkumar Sasidharan, Viktor Stolc, Wei Deng, Hang He, Jan Korbel, Xuewei Chen, Waraporn Tongprasit, Pamela Ronald, Runsheng Chen, Mark Gerstein, Xing Wang Deng. 2007, Global Identification and Characterization of Transcriptionally Active Regions in the Rice Genome. PLoS ONE, 2(3): e294.

16 Young-Su Seo, Mawsheng Chern, Laura E. Bartley, Muho Han, Ki-Hong Jung,Insuk Lee, Harkamal Walia, Xia Xu, Peijian Cao, Wei Bai, Rajeshwari Ramanan,Fawn Amonpant, Loganathan Arul, Patrick E. Canlas, Randy Ruan, Chang-Jin Park,Xuewei Chen, Sohyun Hwang, Jong-Seong Jeon, and Pamela C. Ronald. 2011, Towards Establishment of a Rice Stress Response Interactome. PLoS Genet, 7(4): e1002020.

17 X.W. Chen, S.G. Li, W.X. Zhai, J.C. Xu, Z.Z. Ling, W.M. Wang, X.B. Li, Y.P. Wang, G. Cao, J.J. Shang, Y.Q. Ma, K.D. Zhou, L.H. Zhu. 2004, Identification of Two Blast Resistance Genes in Rice Digu. Jounal of Phytopathology 15277–85

18 Zheng X, Chen X, Zhang X, Lin Z, Shang J, Xu J, Zhai W, Zhu L.2004, Isolation and identification of a gene in response to rice blast disease in rice. Plant Molecular Biology, 54: 99–109

19 Wenxue Zhai, Caiyan Chen, Xuefeng Zhu, Xuewei Chen, Dechun Zhang, Xiaobing Li, Lihuang Zhu. 2004, Analysis of T-DNA- Xa21 loci and bacterial blight resistance effects of the transgene Xa21 intransgenic rice.Theoretic Applied Genetics.109: 534542

20 ZHONG Yiming, JIANG Guanghuai, CHEN Xuewei, XIA Zhihui, LI Xiaobing ZHU Lihuang, ZHAI Wenxue Identification and gene prediction of a 24 kb region containing xa5, a recessive bacterial blight resistance gene in rice (Oryza sativa L.) 2003, Chinese Science Bulletin. 48(1), 2725-2729.

21 Yu, J., , Chen,X., ., and Yang, H. 2002, A draft sequence of the rice genome (Oryza sativa L. ssp. indica).Science. 296, 79-92.

22 CHEN Xuewei, Li Shigui, WANG Wenming, Li Hanyun, ZHOU Kaida, ZHU Lihuang. 2001, Molecular tagging of a genic male-sterile gene MS-P in rice. Chinese Science Bulletin. 46(1),66-69. (In English).

23 YU Jun, HU Songnian, -CHEN Xuewei,-,YANG Huanming. 2001, A draft sequence of the rice (Oryza sativa ssp. indica) genome. Chinese Science Bulletin. 46:1937-1942.

24 W. Wang, W. Zhai, M. Luo, G. Jiang, X. Chen, X. Li, R. A. Wing, L. Zhu. 2001, Chromosome landing at the bacterial blight resistance gene Xa4 locus using a deep coverage rice BAC library., Molecular Genetics and Genomics. 265,118-125.

25 W.M. Wang, W.X. Zhai, G.H. Jiang, X.W. Chen, X.B. Li, L. H. Zhu. 2000, Construction of a BAC contig containing Xa4 locus on Chromosome 11., Rice Genetics Newsletter 17,74-76.

26 Wang Wenmin, ZHOU Yongli, JIANG Guanhuai, MA Bojun, CHEN Xuewei, ZHANG Qi, ZHU Lihuang, ZHAI Wenxue. Fine mapping of the rice bacterial blight resistance gene Xa-4 and its co-segregation marker. 2000, Chinese Science Bulletin. 45(19),1779-1782. (SCI: IF:0.68)

27 W.M. Wang, W.X. Zhai, G.H. Jiang, X.W. Chen, X.B. Li, L. H. Zhu. Construction of a BAC contig containing Xa4 locus on Chromosome 11. 2000, Rice Genetics Newsletter 17,74-76.

28 Xuewei Chen, Li Shigui, Wenming Wang, Hanyun Li, Kaida Zhou, Lihuang Zhu. Molecular mapping of a genic male-sterile gene in rice. 2000, Chinese Science Bulletin. 45(15), 1644-1648. (In Chinese).

29 陈德西,陈学伟,雷财林,马炳田,王玉平,李仕贵. 2010, Pi-d2基因水稻对稻瘟病的抗性分析,中国水稻科学, 24(1) 31-35.

30 樊颖伦,陈学伟,王春连,朱立煌,章琦,赵开军. 2006,水稻抗白叶枯病基因Xa23RFLP标记定位及其STS标记的转化. 作物学报, 32(06)931-935.

31 陈学伟, 李仕贵, 马玉清, 黎汉云, 周开达, 朱立煌. 2004, 水稻抗稻瘟病基因Pi-d(t)1Pi-bPi-ta2的聚合及分子标记选择.生物工程学报.20 (5)708-714.

32 朱雪峰, 陈学伟, 李晓兵, 钱前, 黄大年, 朱立煌, 翟文学. Xa21基因水稻中T-DNA整合的遗传定位. 2002, 遗传学报, 29(10),880-886.

32 王文明, 周永力, 江光怀, 马伯军, 陈学伟, 章琦, 朱立煌, 翟文学. 2000, 水稻抗白叶枯病基因Xa-4的精细定位及其共分离分子标记,科学通报,45(19),1779-1782.

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