太阳集团7237网站

王学贵

学历/学位：研究生/博士

职称/职务：教授

硕导/博导：博士生导师

研究方向：农药毒理学

师资类型：教学科研系列

电子邮箱：wangxuegui@sicau.edu.cn

学习经历：

1996.09-2000.06华中农业大学植物保护本科

2000.09-2003.06华中农业大学农药学硕士

2005.09-2009.06华南农业大学农药学 博士

工作经历：

2003.07-2005.10 四川农业大学太阳集团7237网站 助教

2005.11-2010.12 四川农业大学太阳集团7237网站 讲师

2011.01-2019.12 四川农业大学太阳集团7237网站 副教授

2011.03-2013.10 中国农业大学农学与生物技术学院 博士后

2017.12-2018.11奥本大学（美国）昆虫与植物病理学系访问学者

2020.01-至今 四川农业大学太阳集团7237网站 教授

教学及科研项目指导工作：

承担本科生《杂草学》、《植物化学保护学》等课程；承担研究生《农药学研究前沿》、《有害生物抗药性研究进展》、《农药毒理学》等课程。指导本科生科研兴趣培养和创新性实验10余项，本科生以第一作者发表SCI论文2篇，CSCD论文8篇，参与发表SCI和CSCD论文20余篇；指导本科生获第五届全国大学生生命科学创新创业大赛一等奖和二等奖各一项。

主要研究方向：

农药毒理学。主要从事昆虫的抗药性监测、杀虫剂抗药性机理和抗性治理，以及新杀虫剂的抗药性风险评估等研究，通过克隆和表达与抗性相关的重要基因，利用RNAi、qPCR及CRISPR-Cas9等分子手段，验证其功能，为昆虫的可持续防控提供理论依据。

主持及参与项目：

[1]四川省科技厅重点项目“四川稻区二化螟抗药性监测、抗药性分子快速检测技术及绿色防控体系构建与示范”,项目编号2022YFN0044,起止年限：2022.01-2023.12(主持).

[2]四川省科技厅重点项目“四川省草地贪夜蛾抗药性监测及其抗药性基因分子检测”,项目编号2022YFSY0034,起止年限：2022.01-2023.12(主持).

[3]国家重点研发计划“华南及西南水稻化肥农药减施技术集成研究与示范”子课题,项目编号2018YFD0200300,起止年限：2018.01-2021.06(主持).

[4]国家自然科学基金青年基金:光叶铁仔杀虫活性成分及杀虫机理研究,项目编号31101493,起止年限：2012.01-2014.12(主持).

[5]国家公益性行业（农业）专项“保护地果蔬灰霉病绿色防控技术研究与示范”子课题,项目编号201303025,起止年限：2013.01-2017.12(主持).

[6]中央高校特别资助项目（中国农大博士后项目）：芥子苷与氯虫苯甲酰胺对甜菜夜蛾P450诱导表达研究,项目编号2011JS080,起止年限：2012.01-2013.12(主持).

[7]校县合作项目：峨眉千里光的防除与利用研究,起止年限：2010.07-2012.06(主持).

[8]院企合作项目：药肥的开发与利用研究,起止年限：2012.07-2014.12(主持).

[9]四川省教育厅青年基金：马铃薯抑芽防腐悬浮种衣剂的研究,项目编号10ZB041,起止年限：2011.01-2013.12(主持).

[10]四川省教育厅重点实验室项目：蔬菜蚜虫防除无公害制剂的研究,项目编号07ZS001,起止年限为：2008.01-2010.12(主持).

[11]四川农业大学人才引进项目：茶小绿叶蝉的防控研究,起止年限：2003.07-2006.12(主持).

科研成果及转化情况：

[1]王学贵,陈羿渠,冯晓菲,蒋素容,龚国淑,李沛利,常小丽,杨辉,李庆,杨群芳.发明专利:一种马铃薯抑芽种衣剂及制备方法. 2018.01,中国,专利号：ZL2015 1 0400322.X.

[2]王学贵,沈丽淘,张敏,田孟良,杨继芝,蒋素容,蒋春先,王海建,余慧灵.发明专利:一种防控千里光的组合物、制剂及其应用, 2014.07,中国,专利号:ZL2013 1 0115991.3.

[3]王学贵,李倩,王文明,李庆,杨群芳,余慧灵,郝强,樊晶,李燕.发明专利:光叶铁仔提取物及其制备方法和应用, 2014.09,专利号: ZL 2013 1 0456261.x.

[4]王学贵,王西瑶,沈丽淘,刘帆,龚国淑,李庆,王文明,杨群芳,李沛利,李倩.发明专利:一种马铃薯抑芽悬浮种衣剂及其制备方法, 2014.12,专利号: ZL 2013 1 0110259.7.

[5]王西瑶,刘帆,倪苏,杨先泉,王学贵,黄雪丽,王余明,詹君,刘晨,刘一盛,杨坤强.发明专利:一种马铃薯种薯贮藏方法, 2011.12,中国,专利号: ZL 2010 1 0200853.1.

[6]王西瑶,刘帆,倪苏,杨先泉,王学贵,黄雪丽,詹君,刘晨,彭洁,杨昆.一种用紫茎泽兰延长马铃薯贮藏期的方法: 2011.12,专利号: ZL201010200874.3.

参编教材：

自编校内教材一本《杂草学实验指导书》；参编教材2本：《园艺植物保护学》和《种子种苗学综合实验指导》。

近期发表学术论文：

[1]Li MY,Gong CW, Zhang YZ, Zhao X, Jia Y, Pu J, Liu XM, Xu X,Wang XG*.Differences in susceptibility to chlorantraniliprole betweenChilo suppressalis(Lepidoptera: Crambidae) and two dominant parasitic wasps collected from Sichuan Province, China.Pesticide Biochemistry and Physiology,2022, 185: 105150.

[2]Gong CW, Ruan YW, Zhang YM, Wang QL, Wu YT, Zhan XX, He YF, Liu XX, Liu XM, Pu J,Wang XG*. Resistance ofSogatella furciferato triflumezopyrim mediated with the overexpression ofCYPSF01which was regulated by nuclear receptor USP.Ecotoxicology and Environmental Safety, 2022, 238:117535.

[3]ZhangSR,Gu FC, Du Y, Li XY, Gong CW, Pu J, Liu XM,Wang XG*. Risk assessment and resistance inheritance of triflumezopyrim resistance inLaodelphax striatellus.Pest Management Science, 2022, 78(7):2851–2859.

[4]Gong CW, Wang YM, Huang Q, Xu ZZ, Zhang YM, Hasnain A, Zhan XX, He YF, Zhang TY, Shen LT, Pu J, Muhammad A,Wang XG*.Mafregulatesthe overexpression ofCYP307A1, which isinvolved in thefitness advantage of bistrifluron-resistantSpodopteralitura(Fab.) (Noctuidae: Lepidoptera).Ecotoxicology and Environmental Safety, 2022, 234:113425.

[5]Ruan YW, LiuXX, Gong CW, Zhang YM, Shen LT, Hasnain A, Huang YY*,Wang XG*.Cloning and functional verification ofCYP408A3andCYP6CS3related to chlorpyrifos resistance in theSogatella furcifera(Horváth) (Hemiptera: Delphacidae).Biology, 2021, 10: 795.

[6]Gong CW, Yao XG, Yang QF,Wang XG*, Zhang YM, Wang YM, Shen LT.Fitness costs of chlorantraniliprole resistancerelated to theSeNPFoverexpressionin theSpodoptera exigua(Lepidoptera: Noctuidae). International Journal of Molecular Sciences, 2021, 22: 5027.

[7]Gong CW,Wang XG*, Huang Q , Zhang JY, Zhang YM, Zhan XX, Zhang SR, Hasnain A, Ruan YW, Shen LT.The fitness advantages of bistrifluron resistance related toChitin synthase AinSpodoptera litura(Fab.) (Noctuidae: Lepidoptera).Pest Management Science, 2021, 77(7):3458–3468.

[8]Liu SH, Yao XG, Xiang X, Yang QF,Wang XG, Xin T, Yu SY. Fitness costs associated with chlorantraniliprole resistance inSpodoptera exigua(Lepidoptera: Noctuidae).Pest Management Science, 2021, 77(4):1739–1747.

[9]Ruan YW,Wang XG*, Xiang X, Xu X, Guo YQ, Liu YH, Yin Y, Wu YQ, Cheng QH, Gong CW, Zhang YM, Hasnain A, Shen LT, Jiang CX, Jiang SR.Status of insecticide resistance and biochemical characterization of chlorpyrifos resistance inSogatella furcifera(Hemiptera:Delphacidae) in Sichuan Province, China. Pesticide Biochemistry and Physiology,2021, 171: 104723.

[10]Zhao X, Xu X,Wang XG*, Yin Y, Li MY, Wu YQ, Liu YH, Cheng QH, Gong CW, Shen LT. Mechanisms for multiple resistances in field populations ofrice stem borer,Chilo suppressalis(Lepidoptera: Crambidae) from Sichuan Province, China.Pesticide Biochemistry and Physiology,2021, 171: 104720.

[11]Lin TT, Tang JY, He F, Chen G, Shi YJ,Wang XG, Han S, Li SJ, Zhu TH, Chen LH*.Sexual differences in above- and belowground herbivore resistance between male and female poplars as affected by soil cadmium stress. Science of the Total Environment, 2021, 9(803):150081.

[12]Chen JP, Qin SY, Tang JY, Chen G, Xie JL, Chen LH, Han S,Wang XG, Zhu TH, Liu YG, Lin TT*. Exogenous nitrogen enhances poplar resistance to leaf herbivory and pathogen infection after exposure to soil cadmium stress. Ecotoxicology and Environmental Safety 2021, (208): 111688.

[13]Zhang SR,Wang XG*, Gu FC, Gong CW, Chen L, Zhang YM, Hasnain A, Shen LT, Jiang CX. Sublethal effects of triflumezopyrim on biological traits and detoxification enzyme activities in the small brown planthopper,Laodelphax striatellus(Hemiptera: Delphacidae). Frontiers in Physiology, 2020, 11:261.

[14]Chen L,Wang XG*, Zhang YZ, Yang R, Zhang SR, Xu X, Zhu M, Gong CW, Hasnain A, Shen LT, Jiang CX. The population growth, development and metabolic enzymes of the white-backed planthopper,Sogatella furcifera(Hemiptera: Delphacidae)under thesublethal dose of triflumezopyrim. Chemosphere, 2020,247, 125865.

[15]Lin TT*, Chen JP, Zhou SS, Yu WH, Chen G, Chen LH,Wang XG, Shi HZ, Han S, Zhang F. Testing the elemental defense hypothesis with a woody plant species: Cadmium accumulation protectsPopulus yunnanensisfrom leaf herbivory and pathogen infection. Chemosphere, 2020, 247, 125851.

[16]Wang XG,Ruan YW, Gong CW, Xiang X, Xu X, Zhang YM, Shen LT.Transcriptome analysis ofSogatella furcifera(Homoptera: Delphacidae)in response to sulfoxaflor and functional verification of resistance-related P450 genes.International Journal of Molecular Sciences, 2019, 20: 4573.

[17]Li M, Li T, Liu NN, Raban RR,Wang XG, Akbari OS.Methods for the generation of heritable germline mutations in the disease vectorCulex quinquefasciatususing clustered regularly interspaced short palindrome repeats-associated protein 9. Insect Molecular Biology, 2020, 29(2)：214-220.

[18]Pu QY, Liang J, Shen QQ, Fu JY, Pu ZE, Liu J,Wang XG, Wang Q*. A wheatβ-patchoulene synthase confers resistance against herbivory in transgenic Arabidopsis. Genes, 2019, 10(6): 441.

[19]Huang Q,Wang XG*,Yao XG, Gong CW, Shen LT. Effects of bistrifluron resistance on the biological traits ofSpodoptera litura(Fab.) (Noctuidae Lepidoptera). Ecotoxicology, 2019, 28(3): 323–332.

[20]Xiang X, Liu SH,Wang XG*,Zhang YM, Gong CW, Chen L, Zhang SR, Shen LT. Sublethal effects of sulfoxaflor on population projection and development of the white-backed planthopper,Sogatella furcifera(Hemiptera: Delphacidae). Crop Protection, 2019, 120: 97–102.

[21]Wang XG,Gong CW, Zhao Y, Shen LT. Transcriptome and resistance-related genes analysis ofBotrytis cinereaB05.10 strain to different selective pressures of cyprodinil and fenhexamid.Frontiers in Microbiology, 2018, 9: 2591.

[22]Wang XG,Chen YQ, Gong CW,Yao XG,Jiang CX, Yang QF.Molecular identification of four novel cytochrome P450 genes related to the development of resistance ofSpodoptera exigua(Lepidoptera: Noctuidae)to chlorantraniliprole. Pest Management Science, 2018,74(8): 1938–1952.

[23]Wang XG,Xiang X, YuHL, Liu SH, Yin Y, CuiP, Wu YQ, Yang J, Jiang CX, Yang QF.Monitoring and biochemical characterizationof beta-cypermethrin resistance inSpodoptera exigua(Lepidoptera: Noctuidae) in Sichuan Province, China. Pesticide Biochemistry and Physiology,2018, 146:71–79.

[24]Wang XG, Huang Q, Hao Q, Ran S, Wu YQ, Cui P, Yang J, Jiang CX, Yang QF. Insecticide resistance and enhanced cytochrome P450 monooxygenase activity in field populations ofSpodoptera liturafrom Sichuan, China. Crop Protection, 2018, 106: 110–116.

[25]Wang XG, LiQ, Jiang SR, Li PL, Yang JZ.Chemical composition and insecticidal property ofMyrsine stolonifera(Koidz.) Walker(Family: Myrsinaceae) onMusca domestica(Diptera: Muscidae). Acta Tropica, 2017, 170:70–78.

[26]Liu MG, Jiang CX*, Mao M, Liu C, Li Q,Wang XG, Yang QF, Wang HJ.Effect of the insecticide dinotefuran on the ultrastructure of the flight muscle of femaleSogatella furcifera(Hemiptera: Delphacidae). Journal of Economic Entomology, 2017, 110(2), 632–640.

[27]Li PL, Liu D, Zheng XJ, Chen HB, Gong GS, Zhang M*,Wang XG. First report ofColletotrichum gloeosporioidescausing anthracnose onBauhinia blakeana. Plant Disease, 2016, 100:2165.

[28]Wang XG,Gao XW*, Liang P, Shi XY, Song DL. Induction of cytochrome P450 activity by the interaction of chlorantraniliprole and sinigrin in theSpodoptera exigua(Lepidoptera: Noctuidae). Environmental Entomology, 2016, 42(2): 500–507.

[29]Wang XG,Hao Q, Chen YQ, Jiang SR, Yang QF,Qing L.The effect of chemical composition and bioactivity of several essential oils on yellow mealworm beetle,Tenebrio molitorL. (Coleoptera: Tenebrionidae). Journal of Insect Science, 2015, 15(1): 116–122.

[30]Wang XG, Li Q, Shen LT, Yang JZ, Cheng HB, Jiang SR, Jiang CX, Wang HJ.Fumigant, contact, and repellent activities of essential oils against the darkling beetle,Alphitobius diaperinus. Journal of Insect Science, 2014, 14(75): 1–9.

[31]Gong GS, Liu N, Yang JZ,Wang XG. Over-summering of wheat powdery mildew in Sichuan Province, China. Crop Protection, 2012, 02 (34): 112–118.

[32]Wang XG, Wei XY, Huang XY, Shen LT, Tian YQ, Xu HH*. Insecticidal constructure and bioactivity of compounds fromFicus sarmentosavar.henryi.Journal of Integrative Agriculture, 2011, 10(9): 1402–1409.

[33]Wang XG,Wei XY, Tian YQ, Xu HH*, Shen LT. Antifungal flavonoids fromFicus sarmentosavar.henryi.Agricultural Sciences in China, 2010, 5:102–105.

[34]Gao F, Zhu SA, Wu W,Wang XG, Song L.C19-diterpenoid alkaloids from the roots ofAconitum hemsleyanumvar.hanyuanumand their chemotaxonomy significance.Biochemical Systematics and Ecology, 2010, 38 (5):1052–1055.

[35]贡常委,刘越,马钰,詹小旭,周增梅,朱新成,王学贵*.静电喷雾对农药飘移及沉积分布的影响.四川农业大学学报, 2022, 40(2):220–226.

[36]马钰,贡常委,张韫政,李彬,王学贵*.喷头类型对植保无人飞机低容量喷雾雾滴在稻田冠层沉积分布及防控效果的影响.植物保护学报, 2021, 48(3):518–527.

[37]杨锐,徐翔,王学贵*,贡常委,张韫政,阮彦伟,杨德斌,杨旭东.不同助剂、喷头及喷雾压力对自走式喷杆喷雾机稻田喷雾效果的影响.农药学学报,2021, 23(3): 587–596.

[38]李明阳,姚宇波,徐翔,贡常委,杨旭东,杨德斌,王学贵*.几种水稻对褐飞虱的抗性鉴定及抗性相关次生物质分析.应用昆虫学报,2020, 57(6): 1375–1384.

[39]张钰明,向兴,王学贵*.噻虫嗪对褐飞虱的毒力及解毒代谢酶活性的影响.华南农业大学学报,2020, 41(3): 80–85.

[40]贡常委,马钰,杨锐,阮彦伟,王学贵*,刘越.喷嘴类型对植保无人飞机雾化性能的影响.中国农业科学,2020, 53(12):2385–2398.

[41]冯晓菲,贡常委,王学贵*.四川省草莓主产区灰葡萄孢菌的遗传多样性.菌物学报, 2019, 38(7):1033–1045.

[42]贡常委,秦旖曼,屈劲松,王学贵*.四川省草莓灰霉病菌对咯菌腈的抗性测定及其机制.中国农业科学, 2018,51(22): 4277–4287.

[43]梁炜博,向兴,王学贵*,杨群芳,罗家栋.噻虫啉亚致死剂量对斜纹夜蛾解毒酶系活性与生长繁殖的影响.昆虫学报, 2017, 60(10): 1187–1197.

[44]王学贵,余婷,李倩.光叶铁仔提取物对小菜蛾幼虫生长发育的影响.华南农业大学学报, 2017, 38(5): 61–66.

[45]陈羿渠,向兴,贡常委,王学贵*.氯虫苯甲酰胺亚致死剂量对甜菜夜蛾主要解毒酶活性与生长繁殖的影响.中国农业科学, 2017,50(8):1440–1451.

[46]杨进,殷丽琴,王晓,付绍红,王学贵*,李云,王继胜,邹琼,陶兰蓉,康泽明,唐蓉.４种杀菌剂对油菜根肿病的防治潜力及对幼苗防御酶活性的影响.中国油料作物学报, 2017,39(4):546–550.

[47]王学贵,安万霞,刘书华,秦旖曼,赵雪.不同施药器械对环酰菌胺在番茄叶片上的沉积量及其对灰霉病防治效果的影响.农药学学报,2016, 18(4): 524–529.

[48]王学贵,沈丽淘,姚建洪,刘帆,王西瑶*.几种精油对马铃薯种薯储藏期的生理生化影响.植物保护学报, 2016, 43(2): 300–306.

[49]郝强,黄倩,梁炜博,贡常委,王学贵*.不同温度下斜纹夜蛾的两性生命表.昆虫学报, 2016, 59(6): 654–662.

[50]王学贵,罗维,冯晓菲,赵芸,刘书华,陈诗瑶.不同地区灰霉病菌株对腐霉利的抗性测定及生理生化研究.西南农业学报, 2016,29(6): 1353–1357.

[51]张强,梁韦博,杜雪勇,法艳海,王学贵*.大蒜精油对桃蚜生物活性及生理生化的影响.贵州农业科学, 2016, 44(1): 68–71.

[52]王学贵,余慧灵,梁沛,史雪岩,宋敦伦,高希武*.氯虫苯甲酰胺诱导甜菜夜蛾细胞色素P450基因上调表达.昆虫学报, 2015, 58(3): 281–287.

[53]余慧灵,向兴,袁贵鑫,陈羿渠,王学贵*.溴氰虫酰胺亚致死剂量对甜菜夜蛾生长发育及体内解毒酶活性的影响.昆虫学报, 2015, 58(6): 634–641.

[54]向兴,李雪莲,赵辉,张清,王学贵*.10%烯效唑悬浮种衣剂的研制.农药, 2015,54(11): 79–795.

[55]李倩,王学贵*,莫廷星,余婷,富蓉,张旻.光叶铁仔根和茎化学成分研究.中草药, 2014, 45(20): 2904–2907.

[56]余慧灵,王学贵*,田孟良,李文光,袁勇,王英.峨眉千里光防控药剂的筛选及防治效果的研究[J].湖北农业科学, 2012, 51(21):4776–4779.

[57]王学贵,黎人羽,沈丽淘,张敏*,杨继芝,龚国淑.种植模式、种植密度及施肥水平对小麦白粉病发生的影响.植物保护学报, 2012, 39(2): 185–186.

[58]王学贵,沈丽淘,田永清,徐汉虹*.岩木瓜根皮化学成分研究.林产化学与工业, 2011, 31(1): 77–80.

[59]王学贵,沈丽淘,田永清,徐汉虹*.岩木瓜化学成分的分离、结构鉴定与杀虫活性.昆虫学报, 2010, 53(5): 525–530.

[60]王学贵,魏孝义,沈丽淘,田永清,徐汉虹*.珍珠莲黄酮类化学成分研究.中草药, 2010, 28(4): 22–25.

[61]王学贵,罗明,徐汉虹,杨钟灵,汤克伟,张敏*.氯氟吡氧乙酸异辛酯与百草枯及其混剂对三叶草生理生化的影响.华中农业大学学报, 2010, 29(2): 156–159.

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